Single cell genomics
made simple
Free your discoveries
See our short video explainer (right) or read our SimpleCell™ Technology Overview for an in depth review of how our technology works.
Single cell genomics
made simple
Free your discoveries
See our short video explainer (right) or read our SimpleCell™ Technology Overview for an in depth review of how our technology works.
SimpleCell™ Technology: Here’s how it works.
Our technology
Single cell today: powerful technology, constrained by complexity
Current tools for single cell involve complex laboratory frameworks, such as proprietary instruments, microfluidic or manual emulsions, and combinatorial indexing.
The complexity and cost of these methods significantly constrains the use of single cell for important applications across basic and translational research.
Single cell tomorrow: simple, scalable, solution-phase
CS Genetics has developed a radically new approach to single cell, based on a physical phenomenon called ‘Kinetic Confinement’. Our new platform uses novel molecular indexing reagents to deliver index sequences directly to single cells and Kinetic Confinement to perform high-fidelity indexing of molecules across thousands of cells simultaneously in single-tube, solution-phase reactions.
High-throughput single cell with Kinetic Confinement: the SimpleCell™ platform
The SimpleCell™ platform from CS Genetics leverages two core innovations that make Kinetic Confinement work:
CPair
Cell pairing and indexing reagent - novel, bifunctional indexing reagents that deliver index sequences directly to single cells, and
KCB
Kinetic Confinement Buffer - a novel, bifunctional buffer for heat-activated cell lysis and kinetically-confined single cell indexing.
Kinetic Confinement
High-fidelity and high-sensitivity single cell indexing in solution phase with increasing intensity of Kinetic Confinement
Practical features of Kinetic Confinement
The versatility of Kinetic Confinement enable simple, fast, and flexible single cell experiments, and allows straightforward scaling of experimental designs across multiple orders of magnitude.
For additional information about Kinetic Confinement and the SimpleCell™ platform, please see our bioRxiv pre-print.
